MMV malaria box phenotyped against plasmodium and toxoplasma

A Singapore-India collaborative research project has completed phenotypic screening of MMV Malaria Box, a large collection of potent chemical inhibitors against pathogenic parasites Toxoplasma gondii and Plasmodium falciparum, ...

Hijacker parasite blocked from infiltrating blood

A major international collaboration led by Melbourne researchers has discovered that the world's most widespread malaria parasite infects humans by hijacking a protein the body cannot live without. The researchers were then ...

Multidrug resistant genetic factors in malaria parasites

NUS scientists in collaboration with researchers from Norvatis have discovered two genetic markers in Plasmodium falciparum, the deadliest malaria parasite that can cause it to develop resistance against a new antimalarial ...

Genetic changes help mosquitoes survive pesticide attacks

For decades, chemical pesticides have been the most important way of controlling insects like the Anopheles mosquito species that spreads malaria to humans. Unfortunately, the bugs have fought back, evolving genetic shields ...

Turning pathogens against each other to prevent drug resistance

Limiting a much-needed resource could pit pathogens against one another and prevent the emergence of drug resistance. New research demonstrates that harnessing competition among pathogens inside a patient could extend the ...

How malaria tricks the immune system

Global efforts to eradicate malaria are crucially dependent on scientists' ability to outsmart the malaria parasite. And Plasmodium falciparum is notoriously clever: It is quick to develop resistance against medications and ...

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