A building block for liver fitness in old age

The liver can regenerate even in old age and remains surprisingly fit, even though the chromatin in its cells undergoes major remodeling due to epigenetic changes, as researchers from the Max Planck Institute for Biology ...

The new heroics of RNA in cell differentiation

Scientists are increasingly learning of new reasons to appreciate RNA, and the glycolytic enzyme ENO1 seems to have provided yet another in new research from EMBL this week, as published in Molecular Cell.

Are egg cells in aging primates protected from mutations?

New mutations occur at increasing rates in the mitochondrial genomes of developing egg cells in aging rhesus monkeys, but the increases appear to plateau at a certain age and are not as large as those seen in non-reproductive ...

Genomic regulatory map of the zebrafish

Zebrafish and humans look very different on the outside. Yet about 70 percent of their genes are similar to human genes—including many that can trigger diseases. That makes the animal a popular model organism. Many observations ...

Scientists discover 'bulkheads' between liver cells

Researchers from Skoltech and their colleagues from Germany and the U.S. have discovered structures responsible for the shape of bile canaliculi, a network of canals in the liver. Published in the Journal of Cell Biology, ...

High-throughput metabolic profiling of single cells

Scientists from the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Center (DKFZ) have presented a new method for generating metabolic profiles of individual cells. The method, which combines fluorescence ...

Understanding what drives cell typing

Scientists know that developing cells in a healthy embryo will transform into a variety of cell types that will make up the different organ systems in the human body, a process known as cell differentiation. But they don't ...

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