Penn Engineers have developed a new means of targeting the lungs with lipid nanoparticles (LNPs), the minuscule capsules used by the Moderna and Pfizer-BioNTech COVID-19 vaccines to deliver mRNA, opening the door to novel ...
Bio & Medicine
Mar 1, 2024
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27
Durable repression of a gene that has a role in controlling cholesterol levels, achieved without permanent genome editing, has been demonstrated in a mouse study published in Nature this week.
Biotechnology
Feb 29, 2024
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16
A novel therapeutic strategy developed by researchers at São Paulo State University (UNESP) could revolutionize the treatment of visceral leishmaniasis, a neglected tropical disease (NTD) transmitted by sandflies. Some 12 ...
Bio & Medicine
Feb 20, 2024
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22
Johns Hopkins researchers have identified minuscule particles that supercharge therapeutic cancer vaccines, which train the immune system to attack tumors. These new lipid nanoparticles—tiny structures made of fat—not ...
Bio & Medicine
Dec 14, 2023
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52
Platelet transfusions are essential in managing bleeding and hemostatic dysfunction, and can be expanded to be used as cell therapy for a variety of diseases. The efforts to create such cell therapies require that researchers ...
A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while minimizing off-target ...
Bio & Medicine
Dec 8, 2023
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108
A large Australian team led by Monash University has devised a new approach to killing antibiotic-resistant bacteria using lipid nanoparticles that target specific layers on the surface of the bacterial cell.
Bio & Medicine
Nov 7, 2023
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43
Researchers at Tel Aviv University have destroyed 90% of multiple myeloma blood cancer cells under laboratory conditions, and 60% in human tissues taken from patients at Rabin Medical Center (Belinson Hospital), using an ...
Bio & Medicine
Jul 31, 2023
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89
Researchers at Karolinska Institutet have created a new method of studying the smallest bioparticles in the body. The study, which is published in Nature Biotechnology, has considerable scientific potential, such as in the ...
Bio & Medicine
Jun 12, 2023
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4
Ovarian cancer ranks fifth in cancer deaths among women, accounting for more deaths than any other cancer of the female reproductive system. In a study conducted at Tel Aviv University, researchers used protein CKAP5 (cytoskeleton-associated ...
Bio & Medicine
May 1, 2023
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