The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus ...
Bio & Medicine
Apr 3, 2024
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18
Messenger RNA became a household term when it was used as the backbone of the first COVID-19 vaccines, especially after the Nobel Prize was awarded to two mRNA pioneers at the University of Pennsylvania.
Biotechnology
Apr 3, 2024
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6
For patients with certain types of cancer, CAR T cell therapy has been nothing short of life changing. Developed in part by Carl June, Richard W. Vague Professor at the Perelman School of Medicine, and approved by the Food ...
Bio & Medicine
Mar 25, 2024
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47
A study aiming to develop a lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with ...
Bio & Medicine
Mar 19, 2024
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4
Too often, the lack of clinical trials means that pregnant women suffer because available medications are prescribed off-label for them or not at all. A new study offers proof of concept for the important parameters to develop ...
Bio & Medicine
Mar 8, 2024
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26
Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions ...
Bio & Medicine
Mar 4, 2024
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55
Penn Engineers have developed a new means of targeting the lungs with lipid nanoparticles (LNPs), the minuscule capsules used by the Moderna and Pfizer-BioNTech COVID-19 vaccines to deliver mRNA, opening the door to novel ...
Bio & Medicine
Mar 1, 2024
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27
Durable repression of a gene that has a role in controlling cholesterol levels, achieved without permanent genome editing, has been demonstrated in a mouse study published in Nature this week.
Biotechnology
Feb 29, 2024
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16
A novel therapeutic strategy developed by researchers at São Paulo State University (UNESP) could revolutionize the treatment of visceral leishmaniasis, a neglected tropical disease (NTD) transmitted by sandflies. Some 12 ...
Bio & Medicine
Feb 20, 2024
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22
Johns Hopkins researchers have identified minuscule particles that supercharge therapeutic cancer vaccines, which train the immune system to attack tumors. These new lipid nanoparticles—tiny structures made of fat—not ...
Bio & Medicine
Dec 14, 2023
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