Related topics: type 2 diabetes · insulin resistance

Lipid expansion microscopy uses 'power of click chemistry'

Lipids—fats—make great walls for cells and organelles because they are water resistant and dynamic. But those same characteristics also make them hard to image using expansion microscopy, a technique that works for magnifying ...

New understanding of the inner world of lysosomes

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown factories of cells. The findings, ...

Cross-species cell landscape constructed at single-cell level

Thanks to high-throughput single-cell RNA sequencing (scRNA-seq), it is possible to construct single-cell transcriptomic atlases at the organic level. For example, cell atlases for vertebrate and invertebrate systems have ...

Understanding how microbiota thrive in their human hosts

A research team lead by scientists from the Max Planck Institute for Biology, Tübingen, Germany, has now made substantial progress in understanding how gut bacteria succeed in their human hosts on a molecular level. They ...

From cell fat to cell fate

How does a cell "decide" what type of cell to become? The question of "cell fate" has been explored for decades now, especially in the context of stem cell biology, but there are still gaps in our understanding. For example, ...

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