Embedding iron oxide into liposome bilayer to trigger ferroptosis

Ferroptosis, an iron-dependent regulated cell death process driven by excessive lipid peroxides and membrane injury, can enhance cancer vulnerability to chemotherapy. Lipid peroxidation of unsaturated lipids (UL) in biological ...

How the body's delivery system could lead to targeted therapeutics

In a post-pandemic world, we are used to sending and receiving parcels, getting groceries and items delivered to our door, sending messages and items to loved ones we cannot see. We've become accustomed to sending and receiving ...

Division and growth of synthetic vesicles

One big challenge for the production of synthetic cells is that they must be able to divide to have offspring. In the journal Angewandte Chemie, a team from Heidelberg has now introduced a reproducible division mechanism ...

Structural clues for influenza virus assembly and disassembly

The influenza A virus is surrounded by a lipid bilayer that forms the outermost layer much like the plasma membranes on our own cells. Immediately under this lipid bilayer is a dense protein layer formed from M1 matrix protein. ...

Nanobowls serve up chemotherapy drugs to cancer cells

For decades, scientists have explored the use of liposomes—hollow spheres made of lipid bilayers—to deliver chemotherapy drugs to tumor cells. But drugs can sometimes leak out of liposomes before they reach their destination, ...

What limits the ability of plants to draw water from dry soil?

What limits the ability of plants to draw water from dry soil? That's the question California State University, Fullerton plant biologist H. Jochen Schenk and his collaborators addressed in a study supported by the National ...

Simulations show fundamental interactions inside the cell

Actin filaments have several important functions inside cells. For one, they support the cell membrane by binding to it. However, scientists did not know exactly how the actin interacts with the membrane lipids. Simulations ...

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