Key leukemia defense mechanism discovered

Virginia Commonwealth University Massey Cancer Center researcher Steven Grant, M.D., and a team of VCU Massey researchers have uncovered the mechanism by which leukemia cells trigger a protective response when exposed to ...

Researchers uncover genetic 'bridge' to leukemia progression

For cells to thrive, a complex network of three-dimensional structures assembles to read, copy and produce the genetic materials (DNA) needed for cellular function. Understanding how these structures form, and what happens ...

The point of no return: Chromatin enforces cell fate decisions

Stem cells balance self-renewal with differentiation into mature cells. A fundamental and intriguing question is when during the process of maturation a cell reaches a "point of no return," losing its capacity to self-renew ...

Computer model identifies drug-resistant mutations

To counter drug resistance, scientists engineer new drugs to "fit" new mutations and thus kill the cancer cell or pathogen. Now, an NIBIB-funded team of Penn State engineers has a new approach for predicting which mutation ...

Dual function found for mRNA modifier

A chemical modification of messenger RNA (mRNA) performs different functions depending on its location, according to a study published in the journal Molecular Cell.

New insights into the epigenetic control of hematopoiesis

Scientists at The Wistar Institute have characterized a novel function for the INTS13 protein that is part of a large protein complex regulating gene transcription, called Integrator. According to study results, published ...

page 5 from 5