Coordinated activities of protein kinases and protein phosphatases ensure phosphorylation homeostasis and amplitude of signaling response, and understandably its imbalance is linked to diseases, such as cancer. Unlike with ...
Biochemistry
Mar 15, 2017
0
6
"Kinase inhibitor" drugs, which target a class of enzymes that are crucial to keep cells running, make up one of the great success stories of modern medicine.
Biochemistry
Jan 13, 2017
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3
A new technique that will allow scientists to determine the effects of turning on and off a set of molecules involved in almost every cellular pathway, determine their downstream effects, and uncover new drug targets has ...
Biochemistry
Dec 13, 2016
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395
Researchers at the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have identified a role of receptor tyrosine kinases in the regulation of the cellular mechanosensory machinery, which has relevance ...
Bio & Medicine
Sep 21, 2016
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10
Plants, bacteria and fungi react to light with light-sensitive proteins. Scientists from the University of Gothenburg and their Finnish colleagues from University of Jyväskylä have now determined the inner workings of one ...
Cell & Microbiology
Aug 15, 2016
0
12
It is one of the wonders of nature: multiplying cells are able to precisely copy their genetic material, once and only once, and spatially segregate the resulting two sets of chromosomes when the time comes to separate into ...
Cell & Microbiology
Jul 26, 2016
0
258
Protein kinases, most scientists would agree, regulate nearly every aspect of cell life. It is no surprise, then, that having faulty protein kinases may lead to a number of human conditions, including cardiovascular diseases, ...
Biochemistry
Apr 8, 2016
0
298
Researchers at the University of British Columbia have identified a common ancestral gene that enabled the evolution of advanced life over a billion years ago.
Evolution
Mar 3, 2016
10
956
An international team of researchers, including Kun Yue, Tom Beeckman and Ive De Smet (VIB/UGent), discovered a new cell division regulator that shapes plant root systems, PROTEIN PHOSPHATASE 2A-3 (PP2A-3). Their findings, ...
Biotechnology
Jan 19, 2016
0
6
Scientists have drawn up molecular blueprints of a tiny cellular 'nanomachine', whose evolution is an extraordinary feat of nature, by using one of the brightest X-ray sources on Earth.
Bio & Medicine
Dec 17, 2015
0
63
