Architecture of mTOR protein complex solved

For a long time it has been known that the protein TOR - Target of Rapamycin - controls cell growth and is involved in the development of diseases such as cancer and diabetes. Researchers at the University of Basel's Biozentrum ...

A new model for transmembrane cell-surface receptor activation

"This 'rotation model', which made the cover of BioEssays, represents a true paradigm shift in the membrane receptor field," stated Prof. Pierre De Meyts, a renowned researcher of insulin and receptor binding for almost half ...

Enzyme helps detect foreign DNA

The human immune system responds to DNA from pathogens by triggering the production of a defense molecule known as interferon. A research team led by A*STAR scientists has now pinpointed an enzyme integral to this process, ...

Discovery in plant growth mechanisms opens new research path

New findings reported this week by plant molecular biologists at the University of Massachusetts Amherst are deepening scientists' views of a cell surface regulator, FERONIA receptor kinase from the model plant Arabidopsis, ...

Scientists confirm key targets of new anti-cancer drug candidates

Ribosomes, ancient molecular machines that produce proteins in cells, are required for cell growth in all organisms, accomplishing strikingly complex tasks with apparent ease. But defects in the assembly process and its regulation ...

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