Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and ...
Biochemistry
Mar 20, 2019
0
186
In order for tumors to successfully take hold and spread in the body, they typically must meet several developmental milestones. These include things like suppressing apoptosis, cultivating replication and angiogenesis, weaning ...
A University of Utah-led study using X-rays and neutron beams has revealed the inner workings of a master switch that regulates basic cellular functions, but that also, when mutated, contributes to cancer, cardiovascular ...
Biochemistry
Oct 9, 2014
0
0
The post-translational addition of phosphate groups to serine, threonine and tyrosine residues is a fundamental strategy for regulating protein activities in eukaryotes. Eukaryotic protein kinases—the enzymes that catalyze ...
Cell & Microbiology
Jul 17, 2018
0
6
(PhysOrg.com) -- Two teams of Oxford University researchers led by Professors Judith Armitage and David Stuart have made the first steps towards being able to engineer a bacterial cell that can sense and respond to novel ...
Cell & Microbiology
Feb 9, 2010
0
0
Researchers at the UNC School of Medicine have devised a new biochemical technique that will allow them and other scientists to delve much deeper than ever before into the specific cellular circuitry that keeps us healthy ...
Biochemistry
Mar 9, 2014
0
0
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered how a protein long known to be an essential activator of DNA replication actually triggers this process in cells.
Cell & Microbiology
Jan 7, 2010
0
0
If one wants to better understand how plants grow, one must analyse the chemistry of life in its molecular detail. Michael Hothorn from the Friedrich-Miescher-Laboratory of the Max Planck Society in Tübingen and his team ...
Cell & Microbiology
Aug 8, 2013
0
0
Researchers from the Carl R. Woese Institute for Genomic Biology in collaboration with scientists at Oxford University have published a paper in Cell reporting the function of LanCL proteins. These proteins are found in eukaryotic ...
Cell & Microbiology
Apr 30, 2021
1
67
A set of 10 signaling proteins found in the microbe that causes tuberculosis (TB) play a far larger role in regulating the bacterium's growth, development and behavior than previously thought, according to recent research. ...
Cell & Microbiology
Feb 23, 2023
0
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