Anti-aging molecule NAD+ gets a boost from blocking an enzyme

Nicotinamide adenine dinucleotide (NAD+) is a major player in nutrition today. Studies have shown that NAD+ concentrations decrease during aging and that recovering the body's levels of NAD+ can prolong both health span and ...

Excess phosphorus in cat food damages the kidney

A new study carried out by LMU veterinarians shows that high phosphorus intake, comparable to the average level provided by prepared cat food, can be deleterious to kidney function in healthy cats.

Researchers create a 'living kidney membrane'

Researchers at the MIRA research institute of the University of Twente and the Radboudumc have created a 'living membrane' combining kidney epithelial cells with a polymeric artificial membrane. This achievement is a first ...

Macau female panda Xin Xin dies of kidney failure

The female half of a giant panda couple that the Asian gambling hub of Macau received as a gift from Beijing has died from kidney failure, the southern Chinese city's government said Monday.

Researchers study stem-cell therapy for feline kidney disease

Chronic kidney disease in older cats is the focus of a fifth clinical trial under way at Colorado State University's James L. Voss Veterinary Teaching Hospital, where veterinarians are exploring novel stem-cell therapy that ...

page 1 from 2

Renal function

Renal function, in nephrology, is an indication of the state of the kidney and its role in renal physiology. Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. Both GFR and CCr may be accurately calculated by comparative measurements of substances in the blood and urine, or estimated by formulas using just a blood test result (eGFR and eCCr).

The results of these tests are important in assessing the excretory function of the kidneys. For example, grading of chronic renal insufficiency and dosage of drugs that are primarily excreted via urine are based on GFR (or creatinine clearance).

It is commonly believed to be the amount of liquid filtered out of the blood that gets processed by the kidneys. Physiologically, these quantities (volumetric blood flow and mass removal) are only related loosely.

This text uses material from Wikipedia, licensed under CC BY-SA