Researchers reveal new molecular mechanism for Parkinson's disease risk
In about a fifth of the cases of Parkinson's disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.
In about a fifth of the cases of Parkinson's disease, look to a small, malfunctioning protein in the lysosome as a risk factor, say University of Michigan researchers.
Cell & Microbiology
Jun 23, 2022
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29
EPFL scientists have elucidated for the first time how a notoriously elusive serotonin receptor functions with atom-level detail. The receptor transmits electrical signals in neurons and is involved in various disorders, ...
Biochemistry
Apr 21, 2016
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42
(Phys.org)—The market value for deuterated drugs has recently been estimated at over a billion dollars. Such drugs are simply molecules in which one or more hydrogen atoms are replaced with deuterium. While these kinds ...
The transmembrane protein 206 abbreviated as TMEM206 is an evolutionarily conserved chloride channel that underlies the ubiquitously expressed, proton-activated, outwardly rectifying anion currents. In a new report now published ...
(PhysOrg.com) -- The ability to detect water and regulate water intake is essential for all animals because if cells have too little or too much water the consequences for the animal can be disastrous. It is unclear whether ...
It's not just in toothpaste and mouthwash—fluoride is found in just about everything from rocks and water to the soil and the sea. It is the 13th most abundant element in the Earth's crust, and it's extremely toxic to single-celled ...
Cell & Microbiology
Sep 19, 2013
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A team of researchers affiliated with the Duke University School of Medicine, Lehigh University and the National Institutes of Health has revealed the molecular means by which cold-sensing channels in cells are manipulated ...
Although present almost everywhere - food, soil, toothpaste and especially tap water -, the fluoride ion is highly toxic to microorganisms and cells. To avoid death, cells must remove fluoride that has accumulated inside ...
Biochemistry
Sep 7, 2015
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115
PSI scientists have shed light on an important component of the eye: a protein in the rod cells of the retina which helps us see in dim light. Acting as an ion channel in the cell membrane, the protein is responsible for ...
Molecular & Computational biology
Jan 3, 2022
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363
Plants have a unique ability to safeguard themselves against pathogens by closing their pores—but until now, no one knew quite how they did it. Scientists have known that a flood of calcium into the cells surrounding the ...
Plants & Animals
Aug 26, 2020
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336