During the replication of the SARS-CoV-2 virus, a long string of connected proteins is cleaved apart into individual proteins. This process is interrupted by an FDA-approved drug to treat COVID-19; however, the mechanistic ...
Cell & Microbiology
May 30, 2023
0
49
Like thieves that constantly look for ways to evade capture, Salmonella enterica, a disease-causing bacterium, uses various tactics to escape the human body's defense mechanisms. In a new study, researchers from the Department ...
Cell & Microbiology
May 26, 2023
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49
Using the Australian Synchrotron researchers at the La Trobe Institute for Molecular Science (LIMS) and the French National Research Institute for Agriculture, Food and Environment were able to see the molecular structure ...
Cell & Microbiology
Apr 19, 2023
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103
Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type. HSC transplants can be used to treat conditions where bone marrow is damaged and ...
Cell & Microbiology
Feb 27, 2023
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48
Developing new antifungal treatments is a rising health priority due to an alarming rise in multidrug-resistant fungal "superbugs" that evade medications clinicians have relied on for decades.
Biochemistry
Jan 25, 2023
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60
A new collaborative study from the University of Eastern Finland, Washington University in St. Louis, University of Wisconsin–Madison, University of North Carolina at Chapel Hill and the Promega Corporation discloses the ...
Biochemistry
Nov 28, 2022
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15
Researchers at the University of Illinois Chicago have found a small molecule capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases.
Biochemistry
Oct 25, 2022
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96
A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19. The discovery could lead to the design of critically ...
Molecular & Computational biology
Sep 8, 2022
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65
New structural information about an enzyme target in cancer medicine could help the development of next generation inhibitors. The enzyme, called PARP1, senses DNA damage and sends a cellular signal to carry out repair. PARP1 ...
Biochemistry
Aug 16, 2022
0
65
The first full-length structures of the human angiotensin-converting enzyme (ACE) have been determined by researchers from the University of Cape Town (UCT) using cryo-electron microscopy (cryo-EM). ACE is a blood pressure-regulating ...
Biotechnology
Jul 12, 2022
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40
