Some cancer drugs cause severe side effects because they are not working accurately enough. A team at the University of Würzburg led by biochemist Caroline Kisker has now discovered why.
Biochemistry
Jun 6, 2024
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5
Enhancing drug development for life-threatening diseases like cancer hinges on a deep understanding of protein kinases, making it a focal point for researchers. These enzymes, encoded by more than 500 human genes, serve as ...
Biochemistry
May 24, 2024
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52
Researchers at the Texas A&M School of Veterinary Medicine and Biomedical Sciences (VMBS) have discovered that proton pump inhibitors (PPIs)—medications commonly used to treat heartburn and acid reflux in people and animals—may ...
Veterinary medicine
May 24, 2024
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38
In the human body, molecules known as kinases propagate signals within and between cells, relaying signals that allow cells to respond to changes in the environment. However, there are hundreds of different kinases in the ...
Biochemistry
May 8, 2024
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130
Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.
Cell & Microbiology
Apr 17, 2024
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145
A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study, led by the Swiss Tropical and Public Health Institute (Swiss TPH) and Griffith University's Institute ...
Cell & Microbiology
Apr 3, 2024
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0
Protease inhibitors are a promising strategy for enhancing herbivore resistance in plants, which is crucial for addressing the significant yield losses in crops such as tea plants due to insect herbivores. Serine protease ...
Molecular & Computational biology
Feb 26, 2024
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1
Norwegian University of Science and Technology (NTNU) researchers have developed a promising antibiotic candidate against MRSA. Behind the discovery lies a methodology that may be important in the fight against antimicrobial ...
Cell & Microbiology
Dec 15, 2023
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36
Using nanoparticles administered directly into the cerebrospinal fluid (CSF), a research team has developed a treatment that may overcome significant challenges in treating a particularly deadly brain cancer.
Bio & Medicine
Nov 2, 2023
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65
RUDN University chemists and colleagues from China built several machine learning models and discovered a group of potential drugs that inhibit the enzyme responsible for uncontrolled cell division. The results were published ...
Analytical Chemistry
Sep 26, 2023
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33
