Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells ...
Biochemistry
Feb 16, 2012
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Four new anti-cancer drug leads have been identified in a research paper published online this week in Bioorganic and Medicinal Chemistry.
Biochemistry
Nov 28, 2011
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In a technical tour de force, scientists at Fox Chase Cancer Center have cataloged and cross-indexed the actions of 178 candidate drugs capable of blocking the activity of one or more of 300 enzymes, including enzymes critical ...
Biotechnology
Oct 30, 2011
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Scientists from The Scripps Research Institute have identified a class of compounds that could be a boon to basic research and drug discovery.
Biochemistry
May 15, 2011
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A Purdue University scientist's nanopolymer would make it easier and cheaper for drug developers to test the effectiveness of a widely used class of cancer inhibitors.
Analytical Chemistry
Mar 16, 2011
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A new study suggests that combining two experimental anticancer peptide agents might simultaneously block formation of new tumor blood vessels while also inhibiting the growth of tumor cells.
Biochemistry
Mar 14, 2011
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Providing long-term HIV treatment for over 33 million infected individuals worldwide requires the continuous development of new HIV therapies. Virologists at the Helmholtz Zentrum Munchen have developed a cell-based assay ...
Biochemistry
Dec 1, 2010
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An innovative drug-delivery system - nanoparticles encapsulating nitric oxide or prescription drugs - shows promise for topical treatment of erectile dysfunction (ED), according to a new study by scientists at Albert Einstein ...
Bio & Medicine
Sep 19, 2009
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A research team led by U of T Mississauga scientists has developed a new way to split up a dangerous pair of cancer proteins, a finding that could ultimately lead to chemotherapy that is more effective and has fewer side ...
Biochemistry
Aug 20, 2009
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(PhysOrg.com) -- Flasks, beakers and hot plates may soon be a thing of the past in chemistry labs. Instead of handling a few experiments on a bench top, scientists may simply pop a microchip into a computer and instantly ...
Analytical Chemistry
Aug 3, 2009
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