Scientists said they will reanimate a 30,000-year-old giant virus unearthed in the frozen wastelands of Siberia, and warned climate change may awaken dangerous microscopic pathogens.
Cell & Microbiology
Sep 8, 2015
35
25954
The H5 avian influenza A virus that devastated North American poultry farms in 2014-15 was initially spread by migratory waterfowl, but evidence suggests such highly pathogenic flu viruses do not persist in wild birds. St. ...
Ecology
Jul 25, 2016
0
333
A new way to attack flu viruses is taking shape in laboratories at Rutgers University, where scientists have identified chemical agents that block the virus's ability to replicate itself in cell culture.
Biochemistry
Oct 4, 2013
2
0
Ducks and gulls are the natural hosts of influenza A virus. Ragnhild Tønnessen's PhD research project has characterised influenza A viruses in gulls and ducks in Norway.
Plants & Animals
Sep 12, 2013
0
0
(PhysOrg.com) -- In a study published September 28th ahead of print in the peer-reviewed journal Environmental Health Perspectives, researchers measured oseltamivir carboxylate (OC), the active metabolite of the popular anti-influenza ...
Environment
Oct 1, 2009
1
0
Researchers report for the first time the seroprevalence of three strains of avian influenza viruses in pigs in southern China, but not the H5N1 avian influenza virus. Their research, published online ahead of print in the ...
Cell & Microbiology
Dec 19, 2012
0
0
Many viruses, including HIV and influenza A, mutate so quickly that identifying effective vaccines or treatments is like trying to hit a moving target. A better understanding of viral propagation and evolution in single cells ...
Biochemistry
Aug 20, 2020
0
175
Human cells use a protein named TBC1D5 to route influenza A viruses inside host cells for destruction, preventing the virus from spreading replicated copies of itself to other cells, according to a study published in Nature ...
Cell & Microbiology
Oct 29, 2021
0
83
The influenza A virus, which is responsible for seasonal flu outbreaks, is also the only influenza virus that has previously caused flu pandemics. This makes influenza A an important research topic, as the seasonal flu causes ...
Biochemistry
Jun 6, 2022
0
18
(PhysOrg.com) -- What happens if the next big influenza mutation proves resistant to the available anti-viral drugs? This question was presenting itself to scientists and health officials recently at the World Health Assembly ...
Biochemistry
Jul 6, 2009
3
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Influenzavirus A Influenzavirus B Influenzavirus C Isavirus Thogotovirus
Influenzavirus A is a genus of the Orthomyxoviridae family of viruses. Influenzavirus A includes only one species: Influenza A virus which causes influenza in birds and some mammals. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally viruses are transmitted from wild aquatic birds to domestic poultry and this may cause an outbreak or give rise to human influenza pandemics.
Influenza A viruses are negative sense, single-stranded, segmented RNA viruses. There are several subtypes, labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 16 different H antigens (H1 to H16) and nine different N antigens (N1 to N9). The newest H type (H16) was isolated from black-headed gulls caught in Sweden and the Netherlands in 1999 and reported in the literature in 2005.
Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some pathogenic to one species but not others, some pathogenic to multiple species.
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