From blank round to a potently active substance?

A long-forgotten candidate for antiviral therapy is undergoing a renaissance: Since the 1970s, the small molecule CMA has been considered a potent agent against viral infections, yet it was never approved for clinical use. ...

Wild mice have natural protection against Lyme borreliosis

Like humans, mice can become infected with Borrelia. However, not all mice that come into contact with these bacteria contract the dreaded Lyme disease: Animals with a particular gene variant are immune to the bacteria, as ...

Immunoproteasome crystal structure determined

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells ...

Nobel winners pay tribute to deceased laureate

(AP) -- Two scientists who will collect this year's Nobel Prize in medicine praised late co-winner Ralph Steinman on Tuesday, saying he probably knew he was in line for the prestigious award.

Secrets of plague revealed

In work that is pushing the "diffraction barrier" associated with microscopic imaging of living cells, researchers at Sandia National Laboratories in Albuquerque, NM demonstrated the power of a new super-resolution microscopy ...

Researchers discover how cells recognize viral toxin

(PhysOrg.com) -- For many years it's been known that the fever, achiness and other symptoms you feel during the flu are triggered by a viral molecule that travels through the body acting like a toxin.

New study focuses on protein dynamics

A discovery by associate professor of chemistry and biochemistry Brian Baker and his research group at the University of Notre Dame reveals the importance of dynamic motion by proteins involved in the body's immune response. ...

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