Researchers use base editing to probe blood cell biology
Researchers have used a highly precise genome-editing technology called base editing to make hundreds of direct edits to blood stem cells from patients' bone marrow.
Researchers have used a highly precise genome-editing technology called base editing to make hundreds of direct edits to blood stem cells from patients' bone marrow.
Cell & Microbiology
May 3, 2023
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11
Human skin is home to millions of microbes. One of these microbes, Staphylococcus aureus, is an opportunistic pathogen that can invade patches of skin affected by eczema, also known as atopic dermatitis.
Evolution
Apr 12, 2023
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47
Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract. While we have known for decades that ...
Cell & Microbiology
Apr 11, 2023
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43
M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis. Interestingly, they are characterized by distinct and opposing phenotypes. M1 macrophages are known for their bactericidal and tumoricidal ...
Biochemistry
Mar 28, 2023
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52
Scientists have long known that wild seabirds ingest bits of plastic pollution as they feed, but a study Monday shows the tiny particles don't just clog or transit the stomach but can subvert its complex mix of good and bad ...
Ecology
Mar 27, 2023
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51
Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts is also an essential part of tackling infections that take hold within our cells, like TB.
Cell & Microbiology
Mar 23, 2023
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38
A research team, led by Professor Moeto Nagai and comprised of researchers from the Department of Mechanical Engineering and the Electronic Inspired Interdisciplinary Research Institute (EIIRIS), Toyohashi University of Technology, ...
Cell & Microbiology
Jan 30, 2023
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147
University of Queensland researchers have identified a pathway in cells that could be used to reprogram the body's immune system to fight back against both chronic inflammatory and infectious diseases.
Cell & Microbiology
Jan 18, 2023
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276
In the 1950s, the geneticist J.B.S. Haldane attributed the maintenance or persistence of the mutation responsible for anomalies in red blood cells commonly observed in Africa to the protection these anomalies provided against ...
Evolution
Jan 13, 2023
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102
Researchers at Johns Hopkins Medicine say their new studies suggest that the first pandemic-accelerating mutation in the SARS-CoV-2 virus, which causes COVID-19, evolved as a way to correct vulnerabilities caused by the mutation ...
Cell & Microbiology
Jan 12, 2023
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35