Understanding the entry mechanism of SARS-CoV-2 into human cells

The biology of SARS-CoV-2, the virus behind the COVID-19 pandemic, remains partially elusive. Understanding viral mechanisms is a key factor in developing effective treatment strategies against the outbreak. Now, Keesiang ...

When organoids meet coronaviruses

Researchers from the group of Hans Clevers in collaboration with the group of Bart Haagmans (Erasmus MC) established an organoid biobank to search for the genes that are essential for the spreading of a SARS-CoV2 infection. ...

Possible new antivirals against COVID-19, herpes

In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens. Synthetic peptides could reinforce this defense but don't last long in the body, so researchers are ...

Evolutionary 'arms race' may help keep cell division honest

Eggs and sperm are special cells for many reasons, but one of the characteristics that sets them apart is that unlike other human cells, which have two copies of 23 chromosomes, one from the mother and one from the father, ...

How cells remember inflammation

When a tissue experiences inflammation, its cells remember. Pinning proteins to its genetic material at the height of inflammation, the cells bookmark where they left off in their last tussle. Next exposure, inflammatory ...

New tool aims to fight COVID-19, other diseases

When harmful bacteria or viruses enter the body, immune cells spot telltale proteins known as antigens on the invaders' surfaces and send out armies of antibodies to fend them off. If some of those antibodies have just the ...

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