Related topics: gene therapy

Replication protein A and WAS protein partner to fix damaged DNA

DNA replication and repair happens thousands of times a day in the human body and most of the time, people don't notice when things go wrong thanks to the work of Replication protein A (RPA), the "guardian of the genome." ...

Landing therapeutic genes safely in the human genome

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)." These are ...

Simulations show how to make gene therapy more effective

Diseases with a genetic cause could, in theory, be treated by supplying a correct version of the faulty gene. However, in practice, delivering new genetic material to human cells is difficult. A promising method for the delivery ...

Chinese researchers further develop adenine base editing system

Two research teams from East China Normal University and Sun Yat-Sen University in China have developed and improved the ABE system in mouse and rat strains, which has great implications for human genetic disorders and gene ...

page 2 from 5