Related topics: cells · mouse model · virus · genes · cancer cells

Researchers identify the source of asymmetry in RNA-DNA hybrids

A study headed by the Institute for Research in Biomedicine (IRB Barcelona) and published in the journal CHEM furthers the understanding of the asymmetry between nucleic acid hybrids. This advance may make a significant contribution ...

These molecules could trap viruses inside a cell

Viruses are often used as vehicles for delivery in gene therapy because they're engineered not to damage the cell once they get there, but neglecting to consider how the virus will exit the cell could have consequences.

Scientists find method to boost CRISPR efficiency

Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases.

Nanomachines taught to fight cancer

Scientists from ITMO in collaboration with international colleagues have proposed new DNA-based nanomachines that can be used for gene therapy for cancer. This new invention can greatly contribute to more effective and selective ...

Studying cellular deliveries

Many cells, including cancer cells, are known to secrete short RNAs in tiny vesicles, which then move inside other cells—potentially a form of cell-to-cell communication.

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Gene therapy

Gene therapy is the insertion of genes into an individual's cells and tissues to treat a disease, such as a hereditary disease in which a deleterious mutant allele is replaced with a functional one. Although the technology is still in its infancy, it has been used with some success. Antisense therapy is not strictly a form of gene therapy, but is a genetically-mediated therapy and is often considered together with other methods.

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