Related topics: cells · mouse model · virus · genes · cancer cells

Bacterial viruses: Faithful allies against antibiotic resistance

It is a fact that bacteria are increasingly developing antibiotic resistance. Information campaigns have raised awareness among the general public that the main cause of antibiotic resistance is the high 'selection pressure' ...

Treatment with gene therapy of a new rat model of Morquio A

A research team from the Universitat Autònoma de Barcelona (UAB) has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio ...

Making sense of antisense gene silencing

Gene silencing therapies are used to interfere with, or 'silence', the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies ...

More than one way for animals to survive climate change

As climate change continues to trigger the rise in temperature, increase drier conditions and shift precipitation patterns, adapting to new conditions will be critical for the long-term survival of most species. Researchers ...

New test can detect presence of gene doping in equines

Researchers at the University of Pennsylvania School of Veterinary Medicine (Penn Vet) have successfully developed a new test to systemically detect the local administration of illicit, gene doping therapies in equine athletes. ...

Machine-learning how to create better AAV gene delivery vehicles

Adeno-associated viruses (AAVs) have become promising vehicles for delivering gene therapies to defective tissues in the human body because they are non-pathogenic and can transfer therapeutic DNA into target cells. However, ...

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Gene therapy

Gene therapy is the insertion of genes into an individual's cells and tissues to treat a disease, such as a hereditary disease in which a deleterious mutant allele is replaced with a functional one. Although the technology is still in its infancy, it has been used with some success. Antisense therapy is not strictly a form of gene therapy, but is a genetically-mediated therapy and is often considered together with other methods.

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