Related topics: genome

A new era of mitochondrial genome editing has begun

Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED. TALEDs are base editors ...

DNA nanostructures for targeting cellular surface receptors

A broad subset of parameters, which include cell signaling modulation and receptor binding efficiency, can be explored using programmable DNA nanostructures. Glenn Cremers shows how these structures can uncover important ...

Scientists set out to map the world's genomic diversity

An international consortium of scientists has launched a new effort to create a reference genome that captures the genetic diversity of all the peoples of the world. The researchers describe the initiative, called the Human ...

Repeats are key to understanding humanity's genome

It was like a map of New York missing all of Manhattan. The human reference genome finally has all its blank spots filled in, and seeing everything we missed the first time around is both repetitive—and enlightening.

Scientists make leap forward for genetic sequencing

In a paper published today in Sciences Advances, researchers in the Department of Chemistry and the Department of Physics & Astronomy at the University of California, Irvine revealed new details about a key enzyme that makes ...

Exploring ancient tuberculosis transmission chains

Tuberculosis (TB) is the second most common cause of death worldwide by an infectious pathogen (after Covid-19), but many aspects of its long history with humans remain controversial. Researchers at the Max Planck Institute ...

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