Restricting HIV-1 infection

The HIV-1 capsid protein (CA) interacts with viral factors that support infection and host factors that restrict it. The host protein cyclophilin A (CypA) binds to CA and enhances the action of host restriction factors that ...

Virus exploitscellular waste disposal system

ETH Zurich researchers demonstrate how vaccinia virus manipulates the cellular waste-disposal system and thereby cleverly tricks the cell into assisting the intruders replication. Now, the virologists have turned the tables, ...

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