Scientists crack the code to regenerate plant tissues

Plant regeneration can occur via formation of a mass of pluripotent cells. The process of acquisition of pluripotency involves silencing of genes to remove original tissue memory and priming for activation by external input. ...

Keeping chromosomes in check: A new role for heterochromatin

Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes ...

Energetic gene switch

Histones are proteins that regulate the unwinding of DNA in the cell nucleus and the expression of genes based on chemical modifications or "marks" that are placed on their tails. Understanding how the histone "code" regulates ...

Programming synthetic molecular codes to turn genes 'on'

A team of researchers in Japan developed a synthetic molecular code to script gene activation. The process, described in the Journal of the American Chemical Society, could lead to future gene-based therapies for a wide array ...

BigH1—the key histone for male fertility

Researchers in the Chromatin Structure and Function Lab at the Institute for Research in Biomedicine (IRB Barcelona) have identified the histone BigH1 as a key protein in stem cell differentiation to male sex cells. Histones ...

Researchers discover how gene silencing works in plants

The group of Dr. Myriam Calonje Macaya from the University of Seville,and the group of Franziska Turck from the Max Planck Institute have recently published a study in Genome Biology that advances the knowledge of epigenetic ...

Enzyme key to learning in fruit flies

An animal's reaction to an odor or food or other stimuli depends largely on past experiences and how they have been entered into memory.

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