Reading histone modifications, an oncoprotein is modified in return
Turning genes on and off is an intricate process involving communication between many different types of proteins that interact with DNA.
Turning genes on and off is an intricate process involving communication between many different types of proteins that interact with DNA.
Biochemistry
May 17, 2018
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6
All the trillions of cells in our body share the same genetic information and are derived from a single, fertilized egg. When this initial cell multiplies during fetal development, its daughter cells become more and more ...
Cell & Microbiology
Jan 30, 2018
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210
To Tom Santangelo, single-celled microorganisms called archaea are like ancient mariners, surviving among the most extreme conditions on Earth, including volcanic vents in the deep ocean.
Cell & Microbiology
Nov 8, 2017
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108
Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published ...
Cell & Microbiology
Oct 24, 2017
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10
A fertilized human egg develops into multiple tissues, organs and about 200 distinct cell types. Each cell type has the same genes, but they are expressed differently during development and in mature cells.
Cell & Microbiology
Aug 30, 2017
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199
Chromatin remodelers—protein machines that pack and unpack chromatin, the tightly wound DNA-protein complex in cell nuclei—are essential and powerful regulators for critical cellular processes, such as replication, recombination ...
Cell & Microbiology
Aug 15, 2017
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216
In the cells of palm trees, humans, and some single-celled microorganisms, DNA gets bent the same way. Now, by studying the 3-D structure of proteins bound to DNA in microbes called Archaea, University of Colorado Boulder ...
Cell & Microbiology
Aug 10, 2017
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32
We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.
Cell & Microbiology
May 11, 2017
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9
A group of researchers from the Institute of Bioorganic Chemistry of the RAS and Moscow State University, in collaboration with the University of Utah, has for the first time successfully made use of the FRET microscopy method ...
Cell & Microbiology
Dec 6, 2016
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5
(Phys.org)—A team of researchers with Massachusetts General Hospital, Harvard Medical School and the Broad Institute has developed a procedure to decode histone modifications that point out gene regulation. In their paper ...