After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain ...
Cell & Microbiology
Dec 22, 2022
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25
Researchers have developed a more efficient platform for studying proteins that play a key role in regulating gene expression. The approach uses engineered yeast cells to produce enzyme and histone proteins, conduct biochemical ...
Biochemistry
Jul 1, 2021
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16
The tight wrapping of genomic DNA around nucleosomes in the cell nucleus makes it unavailable for gene expression. A team of Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism that allows chromosomal ...
Biochemistry
May 23, 2013
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0
Plants are incredibly temperature sensitive and can perceive changes of as little as one degree Celsius. Now, a report in the January 8th issue of the journal Cell, a Cell Press publication, shows how they not only 'feel' ...
Cell & Microbiology
Jan 7, 2010
1
0
If you stretched the DNA found in one of your cells from end to end, it would extend approximately 2 meters or 6.5 feet. Every single cell in your body can pack away this much DNA by winding it around proteins called histones. ...
Biochemistry
Dec 19, 2022
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157
A group of researchers from the Institute of Bioorganic Chemistry of the RAS and Moscow State University, in collaboration with the University of Utah, has for the first time successfully made use of the FRET microscopy method ...
Cell & Microbiology
Dec 6, 2016
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5
(PhysOrg.com) -- In the Japanese art of paper folding, a series of folds can make the same sheet of paper into a ballerina or baby elephant. But try unfolding the baby elephant and making it into a ballerina. It’s like ...
Cell & Microbiology
May 14, 2009
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0
An Emory University study shows some of the first direct evidence of a process required for epigenetic reprogramming between generations - a finding that could shed more light on the mechanisms of fertilization, stem-cell ...
Cell & Microbiology
Apr 16, 2009
1
0
The genetic material of our cells—DNA—exists in a high-order structure called chromatin. Chromatin consists of DNA wrapped around histone proteins and efficiently packs DNA into a small volume. Moreover, using a spool ...
Molecular & Computational biology
Jan 23, 2020
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19
For some giant viruses, a DNA-packing trick may be essential for infectivity.
Cell & Microbiology
Jul 27, 2021
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