Boosted mitochondrial capacity safeguards cells under stress

According to a team of plant researchers, mitochondria provide unexpected help for cells in a crisis by respiring away harmful substances. The current study produced by the Institute of Biology and Biotechnology of Plants ...

Illuminating a biological light switch

Using an innovative new imaging technique, researchers at Weill Cornell Medicine have revealed the inner workings of a family of light-sensing molecules in unprecedented detail and speed. The work could inform new strategies ...

High protein diet may harm polar bears

A high protein diet appears linked to kidney disease and shortened lifespans for captive polar bears, a relationship similarly suspected in humans, according to a review led by Washington State University wildlife biologist ...

Deep-learning algorithm aims to accelerate protein engineering

Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and industrial catalysts. To overcome the limitations of naturally occurring proteins, protein ...

New method to analyze nucleosomes

Northwestern Medicine scientists have developed a new method to analyze the protein composition of intact nucleosomes without losing combinatorial information present in chromatin. The technique, called Nuc-MS, could help ...

Screening for macrocyclic peptides

Macrocyclic peptides are promising candidates for pharmaceuticals, but their screening is difficult. Scientists have now developed an easy-to-use, high-throughput screening assay for cyclic peptides with affinity to ubiquitin, ...

Dewdrops on a spiderweb reveal the physics behind cell structures

As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids. However, a tablespoon ...

Understanding COVID-19 infection and possible mutations

The binding of a SARS-CoV-2 virus surface protein spike—a projection from the spherical virus particle—to the human cell surface protein ACE2 is the first step to infection that may lead to COVID-19 disease. Penn State ...

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