In Alzheimer's disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment ...
Cell & Microbiology
Oct 13, 2015
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Protein aggregates that form after a cell is exposed to high, non-lethal temperatures appear to be part of an organized response to stress, and not the accumulation of damaged proteins en route to destruction. Reporting in ...
Cell & Microbiology
Sep 10, 2015
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Cellular repair systems can dissolve aggregated proteins and now Heidelberg researchers have successfully decoded the fundamental mechanism that is key to dissolving these protein aggregates in human cells. Their in-vitro ...
Cell & Microbiology
Aug 12, 2015
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New research from the University of Central Florida has shed light on the workings of a particular protein found in the human body that could have future implications for the treatment of cancer and neurodegenerative conditions.
Biochemistry
Aug 7, 2015
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47
Why offspring cope better with climate change - it's all in the genes!
Environment
Jul 20, 2015
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Small heat shock proteins ensure that other proteins do not clot, allowing the cell to survive stress. Defects in these "small helpers" are associated with medical conditions like cataracts and cancer. Now, scientists at ...
Cell & Microbiology
Jun 11, 2015
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Chaperones are molecular helpers that assist other proteins with folding. One such chaperone is the so-called heat shock protein 60 (Hsp60). This protein forms structures in mitochondria that resemble barrels in which folding ...
Biochemistry
May 12, 2015
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Endangered loggerhead turtles (Caretta caretta) are able to protect themselves against environmental temperature fluctuations while still in the egg, a UWA researcher has discovered.
Ecology
Jan 27, 2015
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Workhorse molecules called heat-shock proteins contribute to refolding proteins that were once misfolded and clumped, causing such disorders as Parkinson's disease, amyotrophic lateral sclerosis, and Alzheimer's disease. ...
Cell & Microbiology
Jan 22, 2015
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"Protein misfolding" diseases such as cystic fibrosis and Alzheimer's may be seriously exacerbated by the body's own response against that misfolding, according to a new study led by scientists at The Scripps Research Institute ...
Cell & Microbiology
Nov 18, 2014
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