Scientists at The Scripps Research Institute (TSRI) have determined the most detailed picture yet of a crucial part of the hepatitis C virus, which the virus uses to infect liver cells. The new data reveal unexpected structural ...
Cell & Microbiology
Nov 28, 2013
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A "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.
Biochemistry
Sep 16, 2013
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All our cells wear a coat of sugar molecules, so-called glycans. ETH Zurich and Empa researchers have now discovered that glycans rearrange water molecules over long distances. This may have an effect on how cells sense each ...
Biochemistry
Jun 18, 2013
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(Phys.org) -- In many biological and pathological processes, glycosidase enzymes attack glycosidic bonds in carbohydrates, glycoproteins, and glycolipids. The ability to modify or block these processes by specific glycosidase ...
Biochemistry
May 29, 2012
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With would-be goblins and ghosts set to drape those huge fake spider webs over doorways and trees for Halloween, scientists in Wyoming are reporting on a long-standing mystery about real spider webs: It is the secret of spider ...
Biochemistry
Oct 21, 2009
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P-glycoprotein (P-gp/ABCB1) is a typical type of multiple drug resistance (MDR) transport protein that can recognize and promote the drug efflux of tumor cells, severely limiting the efficacy of anti-tumor drugs.
Bio & Medicine
May 12, 2023
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Multidrug resistance (MDR)—a process in which tumors become resistant to multiple medicines—is the main cause of failure of cancer chemotherapy. Tumor cells often acquire MDR by boosting their production of proteins that ...
Bio & Medicine
Oct 16, 2020
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Scientists have identified a unique molecular binding mechanism that helps keep non-mammalian creatures in sub-zero temperatures from freezing. Antifreeze glycoproteins (AFGPs), produced by polar fishes, inhibit ice growth ...
Biochemistry
Apr 20, 2018
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Over two weeks in 2004, Song Zhiwei witnessed the slow death of a colony of cells. Song, a bioengineer at the A*STAR Bioprocessing Technology Institute (BTI), had bathed a plate of Chinese hamster ovary cells (CHO) with lectin, ...
Biochemistry
Jun 28, 2017
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6
In the microgravity experiments at the International Space Station (ISS), scientists revealed that supercooled water containing antifreeze glycoproteins accelerates and oscillates its ice crystal growth rate. This seemingly ...
Condensed Matter
Apr 18, 2017
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