A Purdue University biochemist has developed a novel method for detecting certain types of proteins that serve as indicators for cancer and other diseases.
Bio & Medicine
Nov 15, 2016
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182
Multidrug resistance (MDR)—a process in which tumors become resistant to multiple medicines—is the main cause of failure of cancer chemotherapy. Tumor cells often acquire MDR by boosting their production of proteins that ...
Bio & Medicine
Oct 16, 2020
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127
(Phys.org) —A team of researchers working at the Sloan Kettering Institute for Cancer Research has succeeded in building a glycoprotein from scratch. It marks an enormous step forward, the team reports in their paper published ...
A "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.
Biochemistry
Sep 16, 2013
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0
With would-be goblins and ghosts set to drape those huge fake spider webs over doorways and trees for Halloween, scientists in Wyoming are reporting on a long-standing mystery about real spider webs: It is the secret of spider ...
Biochemistry
Oct 21, 2009
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2
Scientists at The Scripps Research Institute (TSRI) have determined the most detailed picture yet of a crucial part of the hepatitis C virus, which the virus uses to infect liver cells. The new data reveal unexpected structural ...
Cell & Microbiology
Nov 28, 2013
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0
Based at the Institute of Chemistry in the Slovak Academy of Sciences, Ján Tkáč's research combines glycomics – the study of sugars in organisms – with biochip sensors based on nanoparticles and nanotubes. The complexity ...
Bio & Medicine
Jun 19, 2013
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0
Cell therapies hold great promise for revolutionizing the treatment of cancers and autoimmune diseases. But this multibillion-dollar industry requires long-term storage of cells at super-cold cryogenic conditions, while ensuring ...
Biochemistry
Feb 14, 2020
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142
Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now.
Biochemistry
May 7, 2018
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217
All our cells wear a coat of sugar molecules, so-called glycans. ETH Zurich and Empa researchers have now discovered that glycans rearrange water molecules over long distances. This may have an effect on how cells sense each ...
Biochemistry
Jun 18, 2013
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0
Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to polypeptide side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known as glycosylation. In proteins that have segments extending extracellularly, the extracellular segments are often glycosylated. Glycoproteins are often important integral membrane proteins, where they play a role in cell–cell interactions. Glycoproteins also occur in the cytosol, but their functions and the pathways producing these modifications in this compartment are less well-understood.
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