A protein that packs massive DNA strands into tiny cells also moonlights as a cleaner of damaged genetic material. This discovery could help detect mitochondrial diseases, which can cause brain damage and organ failure.
Cell & Microbiology
Jul 26, 2023
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1
A collaborative project between the Center for Genome Integrity, within the Institute for Basic Science (IBS, South Korea), and the Dundee School of Life Sciences, the EMBL's European Bioinformatics Institute (EMBL-EBI), ...
Cell & Microbiology
Jun 8, 2020
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7
Whether radiation exposure of fathers can have consequences on their children is one of the most long-standing questions in radiation biology. Using the nematode Caenorhabditis elegans as a model, Professor Dr. Björn Schumacher ...
Molecular & Computational biology
Dec 21, 2022
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33
The Wip1 protein is important for survival, but mutations that inactivate it carry some surprising features. "A lack of Wip1 results in an excessive immune reaction to infectious organisms, in some cases killing the host," ...
Cell & Microbiology
Dec 19, 2012
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As climate change continues to trigger the rise in temperature, increase drier conditions and shift precipitation patterns, adapting to new conditions will be critical for the long-term survival of most species. Researchers ...
Evolution
May 6, 2021
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18
Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...
Cell & Microbiology
Mar 12, 2013
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3
In animals, DNA damage could lead to cancers. Although plants live for a long time without cancers, their growth is always challenged by many environmental factors, such as radiation, salinity, heavy metals and flooding, ...
Molecular & Computational biology
Nov 9, 2022
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10
Cells are generally able to repair spontaneous damage that arises in their genetic material. Unfortunately, the DNA repair process is not perfect and sometimes, damaged DNA gets passed on to newly made cells. A team of researchers ...
Cell & Microbiology
Oct 8, 2014
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0
Living beings are continuously exposed to harmful agents, both exogenous (ultraviolet radiation, polluting gases, etc.) and endogenous (secondary products of cellular metabolism) that can affect DNA integrity. That's why ...
Cell & Microbiology
Jun 17, 2021
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1
RIKEN researchers have developed a highly accurate method for temporarily silencing genes that is promising for advancing biological research and developing new therapies for genetic diseases. The study is published in Nature ...
Biotechnology
Jul 11, 2024
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