In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept ...
Biotechnology
Jul 27, 2023
0
69
In the 1950s, the geneticist J.B.S. Haldane attributed the maintenance or persistence of the mutation responsible for anomalies in red blood cells commonly observed in Africa to the protection these anomalies provided against ...
Evolution
Jan 13, 2023
0
102
The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach ...
Biotechnology
Jun 23, 2022
0
37
The organization of the human genome relies on physics of different states of matter—such as liquid and solid—a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes ...
General Physics
Jun 2, 2021
0
24
Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells. Using a gold nanoparticle instead of an inactivated ...
Materials Science
May 27, 2019
3
193
Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. Activation of the stress response is at the epicentre of the ...
Cell & Microbiology
Feb 22, 2019
0
2
Chinese scientists used an adapted version of a controversial gene-editing technique to correct a disease-causing mutation in human embryos, a medical first cautiously hailed by other experts Thursday.
Biotechnology
Sep 28, 2017
1
116
Computer models developed by Brown University mathematicians show new details of what happens inside a red blood cell affected by sickle cell disease. The researchers said they hope their models, described in an article in ...
Biochemistry
Jul 28, 2017
0
237
It provides the raw material for liquorice candy, calms the stomach and alleviates diseases of the airways: liquorice root. Chosen as the "Medicinal plant 2012", the root has been treasured in traditional healing since ancient ...
Biochemistry
Apr 17, 2012
0
0
Using an innovative gene therapy technique called genome editing that hones in on the precise location of mutated DNA, scientists have treated the blood clotting disorder hemophilia in mice. This is the first time that genome ...
Biotechnology
Jun 26, 2011
2
0
