(Phys.org) —Cellular processes in most organisms are regulated by an internal clock, and proteins called cryptochromes are at the core of its central oscillator. The three dimensional structures of cryptochromes from mouse ...
Cell & Microbiology
Jun 11, 2013
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The crowding of genes inside the nucleus of a cell affects the way they replicate, and how they are turned on and off, according to a study led by the Liggins Institute at the University of Auckland.
Cell & Microbiology
Jan 12, 2016
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The addition and removal of methyl groups on DNA plays an important role in gene regulation. In order to study these mechanisms more precisely, a German team has developed a new method by which specific methylation sites ...
Biochemistry
Nov 24, 2020
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Speciation begins when populations become genetically separated through a substantial reduction in gene flow, and it is at this point that a genetically cohesive set of populations attain the sole property of species: the ...
Biotechnology
Mar 31, 2010
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The packaging of a gene has a major impact on its functional state and must be precisely controlled. A novel blend of methods has unveiled the architecture of a large protein complex that modulates DNA packing, and hints ...
Cell & Microbiology
Sep 16, 2013
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Temperature and dissolved oxygen (DO) can affect a series of physiological and biochemical responses and drive the expression of regulatory genes. When water temperature increases, the solubility of oxygen decreases, leading ...
Plants & Animals
Jan 21, 2022
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For the last eight years, the Genome Aggregation Database (gnomAD) Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more ...
Biotechnology
May 28, 2020
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The DNA contained within each of our cells is exactly the same, yet different types of cells - skin cells, heart cells, brain cells - perform very different functions. The ultimate fate of these cells is encoded not just ...
Cell & Microbiology
Jan 6, 2010
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Wild tomato relatives Solanum habrochaites and S. galapagense are important germplasm donors in modern tomato breeding. Compared to the cultivated tomato, they display many desirable traits, particularly high tolerance to ...
Molecular & Computational biology
Sep 13, 2022
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An international group of researchers led by Carnegie Mellon University physicists Mathias Lösche and Frank Heinrich have established the structure of an important tumor suppressing protein, PTEN. Their findings provide ...
Biochemistry
Aug 20, 2015
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