Substances known as transcription factors often determine how a cell develops as well as which proteins it produces and in what quantities. Transcription factors bind to a section of DNA and control how strongly a gene in ...
Cell & Microbiology
Sep 2, 2016
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105
Almost half our genes can be the starting point for diseases. Scientists have identified 11,000 genes that occur in the human genome in variants that can cause disease. Scientists from the Max Planck Institute for Evolutionary ...
Evolution
Sep 1, 2016
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31
Use of a new technique developed at the Babraham Institute has allowed researchers to take an in-depth look at the gene shuffling process that is responsible for our body's ability to recognise a vast range of foreign agents ...
Cell & Microbiology
Jun 2, 2016
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22
Scientists at Johns Hopkins report they have deciphered the structure and unusual shape of a bacterial protein that prepares segments of DNA for the insertion of so-called jumping genes. The clamshell shape, they say, has ...
Cell & Microbiology
Aug 19, 2015
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433
(Phys.org)—A pair of researchers at MIT has developed what amounts to a "kill switch" for genetically modified organisms (GMOs). In their paper published in the journal Nature Communications, Brian Caliando and Christopher ...
Certain diseases such as cystic fibrosis and muscular dystrophy are linked to genetic mutations that damage the important biological process of rearranging gene sequences in pre-messenger RNA, a procedure called RNA splicing.
Cell & Microbiology
Sep 26, 2013
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2
(Phys.org) —Knowing virtually everything about how the body's cells make transitions from one state to another – for instance, precisely how particular cells develop into multi-cellular organisms – would be a major ...
Cell & Microbiology
Jul 1, 2013
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0
A novel gene associated with canine atopic dermatitis has been identified by a team of researchers led by professors Kerstin Lindblad-Toh, Uppsala university and Åke Hedhammar, SLU, Sweden. The gene encodes a protein called ...
Biotechnology
May 9, 2013
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0
(Phys.org) —Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn't. In the journal Angewandte Chemie, a British team has now introduced a new method that makes ...
Biochemistry
Apr 25, 2013
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0
Blood cells originate from a small pool of hematopoietic stem cells (HSCs) through a complex process of differentiation steps that are tightly regulated at the transcriptional level. Dissecting the mechanisms underlying this ...
Cell & Microbiology
Oct 5, 2012
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0
