Artificially synthesizing genomes has broad prospects in fields such as medical research and developing industrial strains. From the synthesis of the artificial life JCVI-syn1.0 by Craig Venter's team in 2010, to the rewriting ...
Biotechnology
Mar 27, 2023
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33
For many decades, evolutionary biologists assumed that the changes in DNA, known as mutations, occur irrespective of any consequences for the organism. A team led by Professor Detlef Weigel, Director at the Max Planck Institute ...
Evolution
Feb 15, 2022
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11
The cells of female mammals have a dosage problem, because they have twice as many X chromosomes as are needed in the body. Consequently, one of them is randomly selected and switched off already during early embryonic development. ...
Molecular & Computational biology
Jan 5, 2022
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297
New insights into a little-understood DNA structure could provide the basis for new cancer therapies.
Biotechnology
Mar 18, 2021
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54
Researchers led by Kyoto University have reconstituted the human segmentation clock, a key focus of embryonic development research, using induced pluripotent stem cells (iPSCs).
Molecular & Computational biology
Apr 1, 2020
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34
Crispr technology has greatly facilitated gene editing. Associate Professor Thorsten Müller from Ruhr-Universität Bochum and Dr. Hassan Bukhari from Harvard Medical School discuss its pros and cons in a review article in ...
Biotechnology
Sep 17, 2019
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6
Diversity is good, especially when it comes to antibodies. It's long been known that a gene assembly process called V(D)J recombination allows our immune system to mix and match bits of genetic code, generating new antibodies ...
Cell & Microbiology
Sep 13, 2019
0
59
Two teams working independently of one another have identified several CRISPR-Cas12a inhibitors. The first team was made up of members from the University of California, Berkeley, the other had members from Massachusetts ...
Scientists have pinpointed a key gene that controls segmentation during spider development, which reveals a further similarity to the control of segmentation in insects, a study in eLife reports.
Biotechnology
Aug 21, 2018
0
135
A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this highly packaged DNA can be ...
Cell & Microbiology
Jun 28, 2018
0
58
