Researchers led by Kyoto University have reconstituted the human segmentation clock, a key focus of embryonic development research, using induced pluripotent stem cells (iPSCs).
Molecular & Computational biology
Apr 01, 2020
0
34
Crispr technology has greatly facilitated gene editing. Associate Professor Thorsten Müller from Ruhr-Universität Bochum and Dr. Hassan Bukhari from Harvard Medical School discuss its pros and cons in a review article in ...
Biotechnology
Sep 17, 2019
0
6
Diversity is good, especially when it comes to antibodies. It's long been known that a gene assembly process called V(D)J recombination allows our immune system to mix and match bits of genetic code, generating new antibodies ...
Cell & Microbiology
Sep 13, 2019
0
59
Two teams working independently of one another have identified several CRISPR-Cas12a inhibitors. The first team was made up of members from the University of California, Berkeley, the other had members from Massachusetts ...
Scientists have pinpointed a key gene that controls segmentation during spider development, which reveals a further similarity to the control of segmentation in insects, a study in eLife reports.
Biotechnology
Aug 21, 2018
0
135
A tremendous amount of genetic material must be packed into the nucleus of every cell—a tiny compartment. One of the biggest challenges in biology is to understand how certain regions of this highly packaged DNA can be ...
Cell & Microbiology
Jun 28, 2018
0
58
Substances known as transcription factors often determine how a cell develops as well as which proteins it produces and in what quantities. Transcription factors bind to a section of DNA and control how strongly a gene in ...
Cell & Microbiology
Sep 02, 2016
0
105
Almost half our genes can be the starting point for diseases. Scientists have identified 11,000 genes that occur in the human genome in variants that can cause disease. Scientists from the Max Planck Institute for Evolutionary ...
Evolution
Sep 01, 2016
0
31
Use of a new technique developed at the Babraham Institute has allowed researchers to take an in-depth look at the gene shuffling process that is responsible for our body's ability to recognise a vast range of foreign agents ...
Cell & Microbiology
Jun 02, 2016
0
22
Scientists at Johns Hopkins report they have deciphered the structure and unusual shape of a bacterial protein that prepares segments of DNA for the insertion of so-called jumping genes. The clamshell shape, they say, has ...
Cell & Microbiology
Aug 19, 2015
0
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