New CRISPR tool targets RNA in mammalian cells

Researchers from the Broad Institute of MIT and Harvard have shown that a CRISPR-based editing system can cut and bind RNA in mammalian cells. In a paper out this week in Nature, the team used CRISPR-Cas13, which the researchers ...

Lizard blizzard survivors tell story of natural selection

An unusually cold winter in the U.S. in 2014 took a toll on the green anole lizard, a tree-dwelling creature common to the southeastern United States. A new study offers a rare view of natural selection in this species, showing ...

Tweaking the transcriptome to tackle stress

Single-celled plankton known as dinoflagellates are shown to cope with stress using an unexpected strategy of editing their RNA rather than changing gene expression levels.

A snapshot of stem cell expression

Researchers on the Wellcome Genome Campus reveal new genes involved in stem cell pluripotency, new subpopulations of cells and new methods to find meaning in the data. Published in Cell Stem Cell, the findings have implications ...

Scientists develop method for discovering rare cells

Scientists of the Hubrecht Institute Utrecht developed a new method for identifying rare cell types by single-cell mRNA sequencing. The newly developed algorithm, called RaceID, is very useful for identifying rare cell types ...

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