Widespread misinterpretation of gene expression data

Reproducibility is a major challenge in experimental biology, and with the increasing complexity of data generated by genomic-scale techniques this concern is immensely amplified. RNA-seq, one of the most widely used methods ...

Long non-coding RNAs can encode proteins after all

Case Western Reserve School of Medicine scientists have made an extraordinary double discovery. First, they have identified thousands of novel long non-coding ribonucleic acid (lncRNA) transcripts. Second, they have learned ...

Roots to shoots: Hormone transport in plants deciphered

Plant growth is orchestrated by a spectrum of signals from hormones within a plant. A major group of plant hormones called cytokinins originate in the roots of plants, and their journey to growth areas on the stem and in ...

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