The sites where transcription factors bind within regulatory DNA fall into six distinct patterns that overlap with the factors' functions, Broad scientists find, helping advance a goal of regulatory genomics.
Cell & Microbiology
Jul 11, 2018
0
7
Today, biologists add an important discovery to a growing body of data explaining why we're different from chimps and other primate relatives, despite the remarkable similarity of our genes. The new evidence has to do with ...
Evolution
Jan 29, 2018
2
227
A study from Patrick Matthias and his group at the FMI challenges a widely accepted model on how epigenome dynamics control the differentiation of hematopoietic cells. The plasticity of pluripotent stem cells was thought ...
Cell & Microbiology
Oct 20, 2015
0
50
Human existence is basically circadian. Most of us wake in the morning, sleep in the evening, and eat in between. Body temperature, metabolism, and hormone levels all fluctuate throughout the day, and it is increasingly clear ...
Cell & Microbiology
Nov 20, 2014
0
0
Contrary to what was thought, sequences of DNA called enhancers – which control a gene's output – find their targets long before they are activated during embryonic development, scientists at the European Molecular Biology ...
Cell & Microbiology
Jul 3, 2014
0
0
An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers - sequences of DNA that act to amplify the expression of ...
Biotechnology
Mar 24, 2014
0
1
Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and ...
Biotechnology
Oct 13, 2013
1
0
A study conducted by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and the School of Biological Sciences at Nanyang Technological University, Singapore ...
Molecular & Computational biology
Aug 29, 2019
0
6
Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells. These cells continually produce new ones, which appear on the skin surface after a few days. A study led by ICREA ...
Cell & Microbiology
Jul 28, 2016
0
20
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and Stanford University in the USA, have shed new light on how the variations in our molecular make-up, such as gene expression, are controlled ...
Cell & Microbiology
Aug 20, 2015
0
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