DNA structure influences the function of transcription factors

Substances known as transcription factors often determine how a cell develops as well as which proteins it produces and in what quantities. Transcription factors bind to a section of DNA and control how strongly a gene in ...

A guide to CRISPR gene activation

The CRISPR-Cas9 system has come to be known as the quintessential tool that allows researchers to edit the DNA sequences of many organisms and cell types. However, scientists are also increasingly recognizing that it can ...

Math points to 100-times faster mapping of gene activity

New research by UCSF scientists could accelerate – by 10 to 100-fold – the pace of many efforts to profile gene activity, ranging from basic research into how to build new tissues from stem cells to clinical efforts to ...

Modeling tool IDs genes that control stress response in plants

An interdisciplinary team of researchers from North Carolina State University and University of California, Davis has developed a modeling algorithm that is able to identify genes associated with specific biological functions ...

Scientists unveil sex-linked control of genes

Many proteins interact with an RNA molecule called Xist to coat and silence one X chromosome in every female cell. Learning how genes are targeted and silenced may help researchers studying sex-specific diseases.

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