Controlling gene activity in human development

Researchers at the Babraham Institute have revealed a new understanding of the molecular switches that control gene activity in human embryonic stem cells. This insight provides new avenues for improving the efficiency of ...

New coral research exposes genomic underpinnings of adaptation

Scientists at The University of Texas at Austin have observed for the first time that separate populations of the same species—in this case, coral—can diverge in their capacity to regulate genes when adapting to their ...

DNA structure influences the function of transcription factors

Substances known as transcription factors often determine how a cell develops as well as which proteins it produces and in what quantities. Transcription factors bind to a section of DNA and control how strongly a gene in ...

A guide to CRISPR gene activation

The CRISPR-Cas9 system has come to be known as the quintessential tool that allows researchers to edit the DNA sequences of many organisms and cell types. However, scientists are also increasingly recognizing that it can ...

Venus flytrap exploits plant defenses in carnivorous lifestyle

Venus flytraps have fascinated biologists for centuries, however, the molecular underpinnings of their carnivorous lifestyle remain largely unknown. In a study published online today in Genome Research, researchers characterized ...

Math points to 100-times faster mapping of gene activity

New research by UCSF scientists could accelerate – by 10 to 100-fold – the pace of many efforts to profile gene activity, ranging from basic research into how to build new tissues from stem cells to clinical efforts to ...

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