(Phys.org)—The market value for deuterated drugs has recently been estimated at over a billion dollars. Such drugs are simply molecules in which one or more hydrogen atoms are replaced with deuterium. While these kinds ...
Researchers have developed a light-activated tool to show how drugs need to be adapted to combat type 2 diabetes.
Biochemistry
Apr 11, 2016
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G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular ...
Cell & Microbiology
Sep 9, 2014
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In plants, the growth of organs such as roots, leaves and flowers depends upon the activity of meristems. These reservoir-like compartments hold stem cells, which have the ability to develop into various different cell types.
Biotechnology
Sep 11, 2013
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"Pain begone!" In order to send out this signal, the human body produces tiny messenger molecules that dock to certain receptors. Using traditional biochemical methods, this interaction between the messengers, so-called enkephalins, ...
Biochemistry
Jul 9, 2013
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Last year's Nobel Prize in Chemistry – shared by Stanford School of Medicine Professor Brian Kobilka and Robert Lefkowitz of Duke University – recognized groundbreaking research in G protein-coupled receptors (GPCRs). ...
General Physics
May 10, 2013
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A three-dimensional image of one of the proteins that serves as an on-off switch as it binds to receptors on the surface of a cell suggests there may be a sort of main power switch that could be tripped. These surface receptors ...
Biotechnology
Apr 21, 2013
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Researchers at the Ruhr Universität Bochum have developed a new method for attaching proteins to the surface of germanium crystals – for the first time also membrane proteins. This enables time-resolved tracking of the ...
Materials Science
Mar 8, 2013
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(Phys.org)—A research team at Weill Cornell Medical College has solved the 3D crystal structure of a member protein in one of the most important classes of human proteins—the G protein-coupled receptors (GPCRs). These ...
Cell & Microbiology
Feb 27, 2013
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The last time you popped a pill for a headache or a stuffy nose, did you think about how the medication actually alleviates your pain or unblocks your stuffy nose? Curing a disease is a complex process and involves understanding ...
Biochemistry
Jan 14, 2013
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