G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in our cells, involved in signal transmission across the cell membrane. One of the biggest questions is how a signal recognized at the extracellular ...
Cell & Microbiology
Sep 9, 2014
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In plants, the growth of organs such as roots, leaves and flowers depends upon the activity of meristems. These reservoir-like compartments hold stem cells, which have the ability to develop into various different cell types.
Biotechnology
Sep 11, 2013
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A three-dimensional image of one of the proteins that serves as an on-off switch as it binds to receptors on the surface of a cell suggests there may be a sort of main power switch that could be tripped. These surface receptors ...
Biotechnology
Apr 21, 2013
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(Phys.org)—A research team at Weill Cornell Medical College has solved the 3D crystal structure of a member protein in one of the most important classes of human proteins—the G protein-coupled receptors (GPCRs). These ...
Cell & Microbiology
Feb 27, 2013
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The last time you popped a pill for a headache or a stuffy nose, did you think about how the medication actually alleviates your pain or unblocks your stuffy nose? Curing a disease is a complex process and involves understanding ...
Biochemistry
Jan 14, 2013
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Readers of the top-ranked scientific journals Science and Nature might have noticed a recent wave of articles, most recently in the July 13, 2012 issue of Science, with deep importance for biology and medicine. These papers, ...
Cell & Microbiology
Jul 12, 2012
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(PhysOrg.com) -- New information that could help in the fight against asthma has been obtained by an international collaboration of scientists utilizing the U.S. Department of Energy’s Advanced Photon Source at Argonne ...
Biochemistry
Mar 18, 2011
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"Pain begone!" In order to send out this signal, the human body produces tiny messenger molecules that dock to certain receptors. Using traditional biochemical methods, this interaction between the messengers, so-called enkephalins, ...
Biochemistry
Jul 9, 2013
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Last year's Nobel Prize in Chemistry – shared by Stanford School of Medicine Professor Brian Kobilka and Robert Lefkowitz of Duke University – recognized groundbreaking research in G protein-coupled receptors (GPCRs). ...
General Physics
May 10, 2013
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For most of the 20th century, scientists were puzzled by how cells in our body are able to sense and react to external conditions.
Biochemistry
Oct 10, 2012
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