Folding proteins feel the heat, and cold
It's a long-standing assumption that the presence of water influences how proteins fold. A new study is challenging the details.
Materials Science
Nov 11, 2020
0
161
News tagged with folding
Repairing the photosynthetic enzyme Rubisco
Manajit Hayer-Hartl, head of the research group "Chaperonin-assisted Protein Folding," has a long-standing interest in the central enzyme of photosynthesis called Rubisco. Her team has already reported on many of the interacting ...
Biotechnology
Oct 20, 2020
0
133
Old methods prove true for studying proteins
A fresh new look at an old technique in protein biochemistry has shown that it should be reintroduced to the spectroscopy toolkit.
Molecular & Computational biology
Oct 19, 2020
0
11
S-glutathionylation of human-inducible Hsp70 reveals regulatory mechanism involving C-terminal α-helical lid
Heat shock protein 70 (Hsp70) proteins are a family of ancient and conserved molecular chaperones. They play an essential role in maintaining protein homeostasis, including facilitating protein folding and degradation, preventing ...
Biochemistry
Jul 27, 2020
0
10
X-ray scattering shines light on protein folding
KAIST researchers have used an X-ray method to track how proteins fold, which could improve computer simulations of this process, with implications for understanding diseases and improving drug discovery. Their findings were ...
Molecular & Computational biology
Jul 9, 2020
0
27
Scientists uncover new mechanism for balancing protein stability during neuronal development
A research team led by Dr. Chaogu Zheng from the School of Biological Sciences at the University of Hong Kong (HKU), in collaboration with a team led by Professor Martin Chalfie (2008 Nobel Laureate in Chemistry) from the ...
Cell & Microbiology
Jun 16, 2020
0
3
Simulations on biologically relevant time scales achieved
Molecular dynamics simulations (MD) have become a ubiquitous tool in modern life sciences. In these simulations, the interactions between atoms and molecules and their resulting spatial movements are iteratively calculated ...
Cell & Microbiology
Jun 10, 2020
0
9
Hidden symmetry found in chemical kinetic equations
Rice University researchers have discovered a hidden symmetry in the chemical kinetic equations scientists have long used to model and study many of the chemical processes essential for life.
Biochemistry
Apr 30, 2020
0
2512
Nanopore reveals shape-shifting enzyme linked to catalysis
University of Groningen scientists have observed the characteristics of a single enzyme inside a nanopore. They learned that the enzyme can exist in four different folded states, or conformers, that play an active role in ...
Biochemistry
Apr 6, 2020
0
27
Composing new proteins with artificial intelligence
Proteins are the building blocks of life, and consequently, scientists have long studied how they can improve proteins and design completely new proteins that perform new functions and processes.
Biotechnology
Mar 17, 2020
1
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