FRET-based biosensor visualizes execution of necroptosis in vivo

Necroptosis is a form of regulated cell death (RCD) similar to apoptosis, the most commonly studied type of RCD. In contrast to apoptosis, plasma membrane rupture in necroptotic cells occurs at early time points. For this ...

Scientists reveal how detergents actually work

Scientists have discovered the precise way detergents break biological membranes, which could increase our understanding of how soaps work to kill viruses like COVID-19.

How a shape-shifting receptor influences cell growth

Receptors found on cell surfaces bind to hormones, proteins, and other molecules, helping cells respond to their environment. MIT chemists have now discovered how one of these receptors changes its shape when it binds to ...

Cancer-promoting Ras protein exists in a pair within cells

Researchers from Bochum and Osnabrück have gained new insights into the structure of the Ras protein, which acts as a molecular switch for cell growth and is involved in the development of cancer. With the help of fluorescence ...

Synthetic compound provides fast screening for potential drugs

A simple assay may benefit drug discovery for treating diabetes, Parkinson's, and Alzheimers disease, as well as studies of functional food and endocrine disruptor report researchers at Okayama University in the Journal of ...

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