Toggling the functions of a protein that regulates gene expression during cellular reprogramming ensures cell fate conversion, an A*STAR study has found.
Cell & Microbiology
Nov 16, 2018
0
7
The development of an adult organism starts with a fertilized egg that differentiates into hundreds of specialized cell types comprising tissues and organs. How these cell fate changes happen is a subject of research interest. ...
Cell & Microbiology
Oct 3, 2018
0
9
As plants stretch toward the summer sun, they are marching toward one of the most important decisions of their lives—when to flower. Too early, and they might miss out on key pollinators. Too late, and an early frost could ...
Biotechnology
Aug 6, 2018
0
77
Scientists often talk about cell fate and commitment in terms of mechanisms that control gene expression (transcription factors, chromatin remodeling, etc.). But by studying Diamond-Blackfan anemia (DBA), rare genetic blood ...
Cell & Microbiology
Mar 19, 2018
0
22
Both cell type and developmental stage can be deduced from measurements of chromatin accessibility in thousands of single cells, researchers at EMBL and the University of Washington show. They used this approach to uncover ...
Cell & Microbiology
Mar 14, 2018
0
19
St. Jude Children's Research Hospital scientists have determined how a protein's disordered region serves as a molecular rheostat to help regulate cell survival.
Biochemistry
Mar 6, 2018
0
60
The average human has about 37.2 trillion cells. But cells are differentiated for thousands of different functions. How does a cell 'know' which function to fulfill? In a paper published today in Developmental Cell, the group ...
Cell & Microbiology
Oct 12, 2017
0
2
Random differences between cells early in development could be the key to making different cells in the body, according to new research from a team co-led by Professor Wolf Reik. Different cell types - brain, blood, skin, ...
Cell & Microbiology
Aug 1, 2017
0
28
Researchers at the University of Wisconsin-Madison have developed a novel strategy to reprogram cells from one type to another in a more efficient and less biased manner than previous methods.
Cell & Microbiology
Dec 5, 2016
0
201
The fate of over 64,000 live wild animals officially reported to have been confiscated by enforcement agencies remains untraceable, according to a new report released by the University of Oxford Wildlife Conservation Research ...
Ecology
Sep 23, 2016
0
11
