Simulating the shear destruction of red blood cells

Many medical devices for treating heart failure generate nonphysiological shear flow. This can trigger the destruction of red blood cells after implantation of ventricular assist devices (VADs), artificial heart valves, vascular ...

How heart failure disrupts the cell's mitochondria

Chronic heart failure causes the cell's powerhouses to malfunction, in part due to overconsumption of an important intermediary compound in energy production. Supplementing the diet to compensate for this could prove a promising ...

Scotland's first farmers didn't need manure

Early farming in Scotland was a less smelly affair than elsewhere, as new research shows they did not need to use manure to fertilize their fields—unlike their counterparts in other parts of the British Isles and on mainland ...

The priorities for food-security research under extreme events

Fixing hunger is as challenging as ever. Many food producers, including farmers, hunters and fishers are food-insecure; meaning they're not always sure where their next meal will come from. More than 50% of the roughly 600 ...

A key step toward growing human kidneys in the laboratory

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world. Being able to grow working kidney tissue in a laboratory could help accelerate medical treatments ...

Low-cost disease diagnosis by mapping heart sounds

Aortic valve stenosis occurs when the aortic valve narrows, constricting blood flow from the heart through the artery and to the entire body. In severe cases, it can lead to heart failure. Identifying the condition can be ...

Research team first to develop 3D structure of twinkle protein

Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...

Newly identified compound binds to Shiga toxin to reduce its toxicity

A strain of E. coli bacteria called enterohemorrhagic E. coli (EHEC) is known to cause several gastrointestinal disorders, which include bloody diarrhea and abdominal cramps, by damaging the intestinal lining. When accompanied ...

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