Mouse epigenetic aging clock uncovered

Ageing in humans (and animals) can be seen as either an inevitable process of wear and tear or as an inherent biological programme by which the lifespan of each species is more or less predetermined. Recent research has shown ...

'Molecular scissors' could point the way to genetic cures

Guan-En Graham is determined to find out exactly what happened to her father. When she was a child, he developed brain cancer. Since then, she has worked to understand the intricate genetic mechanisms that trigger brain diseases ...

Epigenetics in wild guinea pigs

Fathers are able to adjust to increasing temperatures within their own lifetime and do transmit this information to their offspring. This has now been shown for the first time in a wild animal. The findings were the result ...

New insights into cooperativity in gene regulation

In a study published in Nature, Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) describe how the interplay between transcription factors and epigenetic modifications of DNA ...

Understanding the molecular origin of epigenetic markers

Researchers at the Institute for Research in Biomedicine (IRB Barcelona), Cambridge University and New York University, led by Modesto Orozco, Group Leader at IRB Barcelona, Director of Life Sciences at the Barcelona Supercomputing ...

New tool brings standards to epigenetic studies

One of the most widely used tools in epigenetics research - the study of how DNA packaging affects gene expression - is chromatin immunoprecipitation (ChIP), a technique that allows researchers to examine interactions between ...

Epigenetic 'switch' regulates RNA-protein interactions

Chemical changes - also known as epigenetic modifications - to messenger RNA (mRNA) are thought to play an important role in gene expression, and have recently been found to affect biological processes such as circadian clock ...

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