Cancer cells hijack the 3D structure of DNA

In cancer, a lot of biology goes awry: Genes mutate, molecular processes change dramatically, and cells proliferate uncontrollably to form entirely new tissues that we call tumors. Multiple things go wrong at different levels, ...

Cause of oversized placentas in cloning found after two decades

One reason a technique for cloning animals often results in oversized placentas, and hence failed births, has been uncovered in mice by an all-RIKEN team. This finding will help improve the success rate of the cloning method ...

Chromosome organization emerges from 1-D patterns

The DNA in a human cell is 2 yards (1.83 meters) long and wraps around millions of bead-like histone proteins to fit inside the cell's nucleus. Researchers at Rice University and Baylor College of Medicine showed that examining ...

An epigenetic key to unlock behavior change

When it comes to behaviour, researchers have moved beyond the "nature versus nurture" debate. It's understood that genes and environment both play a role. However, how they interact at a molecular level to shape behaviour ...

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