Before DNA can be transcribed into RNA, an early step in turning the genetic template into protein, the nucleus must first assemble a molecular machine called the pre-initiation complex (PIC), capable of unzipping the double ...
Cell & Microbiology
Dec 2, 2014
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0
Gene transcription is the process by which DNA is copied and synthesized as messenger RNA (mRNA)—which delivers its genetic blueprints to the cell's protein-making machinery.
Cell & Microbiology
May 26, 2016
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8
A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19. The discovery could lead to the design of critically ...
Molecular & Computational biology
Sep 8, 2022
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65
Genes contain all the information needed for the functioning of cells, tissues and organs. Gene expression, meaning when and how the genes are read and executed, is thoroughly regulated like an assembly line with several ...
Cell & Microbiology
Jan 9, 2019
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4
Genes are the carriers of our genetic information. They are read in our cells and used to produce ribonucleic acids (RNAs). During this process, termed transcription, the enzyme RNA polymerase II has a decisive influence ...
Molecular & Computational biology
May 4, 2022
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39
Transcription is the process of synthesizing messenger RNA by RNA polymerase based on the DNA sequence of a gene and is the initial step in gene expression. In bacteria, σ factor is a key component of RNA polymerase for ...
Biotechnology
May 20, 2019
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7
DNA is a blueprint for cells to make proteins that allow those cells to function properly. To create the proteins, enzymes copy genetic codes from DNA strands and then transfer the instructions onto RNA in a process called ...
Biotechnology
Apr 24, 2018
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