The influenza A viruses, which are responsible for deadly pandemics in the past, still remain a major global public health problem today. Molecules known as virulence factors are produced by bacteria, viruses, and fungi to ...
Biochemistry
May 20, 2019
0
6
Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. In a study published ...
Bio & Medicine
Feb 28, 2024
0
11
Tsuruta et al. find that a lipid kinase directs a voltage-gated calcium channel's degradation to save neurons from a lethal dose of overexcitement. The study appears in the October 19, 2009 issue of the Journal of Cell Biology ...
Cell & Microbiology
Oct 19, 2009
0
0
Body cells are workshops that continuously operate to produce and process substances to maintain metabolism. When a substance enters a cell for processing, it is surrounded by a portion of the cell's outer membrane to form ...
Cell & Microbiology
Nov 15, 2019
0
6
The endosome has highly dynamic motility and frequently undergoes fission and fusion events to coordinate endocytic trafficking. Endosome fission has been reported to be associated with cargo sorting. After internalization, ...
Cell & Microbiology
Jul 1, 2021
0
8
Ion channels in the membrane vesicles that mediate intracellular protein transport play a crucial role in cell physiology. A method developed by an Ludwig-Maximilians-Universitaet (LMU) in Munich team now allows them to be ...
Biochemistry
Jul 21, 2017
0
2
Our cells are rich in proteins which are potential targets for therapy. But study of these proteins' behavior, using externally delivered biomacromolecules, has often been stymied by the difficulty of gaining access to the ...
Biochemistry
May 24, 2017
0
8
The endosome is an essential organelle located at the center of membrane traffic and mainly sorts plasma membrane proteins internalized by endocytosis in cooperation with ubiquitination, especially lysine-63-linked polyubiquitin ...
Cell & Microbiology
Jan 22, 2024
0
0
In many ways, a cell is like a city. Proteins or people do daily work to keep the economy going, and items are imported and exported for trade. Imports are shipped into cells by way of endocytosis. Before reaching their final ...
Cell & Microbiology
Jun 27, 2019
0
0
Cells intake substances from the outside world by encapsulating them in vesicles called endosomes, which are subsequently transported throughout the cell. During the transport process, vesicles fuse with other intracellular ...
Cell & Microbiology
Apr 8, 2024
0
17
